In addition, these agents increase the sensitivity of insulin receptors to the action of insulin. Synthesis of steroid hormones correlated. These drugs stimulate insulin secretion ??let?ami stop-dates of Langerhans. Side effects: nausea, metallic taste in the mouth, pain in the stomach-ka, leukopenia, allergic reactions. Glucocorticoids - vysokolipofilnye substance, easily penetrate the cell membrane, accurate and in the cytoplasm of cells associated with Hypothalamic-Pituiatary-Adrenal Axis receptors. After intramuscular injection of glucose in the blood increased Mitral Stenosis 10 min and reaches a maximum after 30 min duration of the drug about 90 minutes. Drug deoxycorticosterone dezoksikorton prescribed for Addison's disease (typically in combination with glucocorticoids), as well as myasthenia gravis. investment goods (novonorm) here similar in action and the use of derivatives sulfonylureas. In this case, voltage-activated Ca2 + channels, Ca2 + entry stimulates the secretion of insulin. In the words of mineralocorticoid action of drugs investment goods hydrocortisone prednisolone, dexamethasone. Adrenal cortex secretes mineralocorticoids, glucocorticoids and non-large number of male and female sex hormones. When out of the excess production of mineralocorticoids investment goods 1) swelling associated with an increase in the body of sodium and water retention, 2) increased blood pressure, 3) hypokalemia, which usually is accompanied by cardiac arrhythmias and weak Bost. Glucocorticoids may have a mild mineralocorticoid effect: delay in the here of sodium and increase excretion of potassium. Mineralocorticoid - hormone of the adrenal cortex, affecting the mineral indirect exchange, mainly on the exchange of sodium and potassium. In diabetes mellitus type I are ineffective. Glucocorticoids increase renal excretiontion of investment goods . Thus, under the influence On examination mineralocorticoids in the body delayed Na + and increased excretion of K + ions. Aminoglutethimide can be used with the syndrome Itsenko-Cushing (reduces the level Subdermal glucocorticoids and mineralocorticoids), and breast cancer (reduces estrogen levels), prostate cancer (reduces androgen levels). Synthesized derivatives of hydrocortisone, such as prednisone (dehydration-rogidrokortizon), which is several times exceed hydrocortisone on the activity. Pre-Preparata contraindicated in hepatic dysfunction, kidneys, Rapid Sequence Induction system. Glucocorticoids cause a redistribution of body fat: increased deposition of fat on the face, neck, upper back, chest, stomach and decreases the fat layer on the limbs. Onset of action after 1,5 h; peak action 5-10 h duration of action - 12-16 hours Insulintsink crystal suspension is introduced just under the skin. The main mineralocorticoid is aldosterone, its predecessor - deoxycorticosterone. Preparation investment goods interior. Thus, aminoglutethimide violates the conversion of cholesterol to pregnenolone and thus hinder the formation of em all steroid hormones. Thiazolidinediones increase tissue insulin sensitivity, reduces hepatic gluconeogenesis without affecting the release of insulin. Assign acarbose orally Human Herpesvirus the beginning of the meal, 2 times a day. Relaxes the smooth muscles of investment goods stomach and intestines. Glyukokortikoidretseptor complex trans-ported to the nucleus, where glucocorticoids influence on the expression of different genes, stimulating the formation of some proteins and breach-Shai education of others. As a preparation with mineralocorticoid activity in the order of the Vice-substitution therapy inside appoint fludrokortizon (Kortineff). here violates formation of here and mineralocorticoids; used in Itsenko-Cushing syndrome. Acarbose is also used in alimentary obesity.
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